Derivatization-assisted dual-mode colorimetric and fluorometric detection of dopamine using 4-hexyl resorcinol

Mohamed N. Goda; Laila S. Alqarni; Faisal K. Algethami; Hossieny Ibrahim; Al‐Montaser Bellah H. Ali; Ramadan Ali; Mohamed M. El-Wekil

doi:10.1039/d6ra02276f

January 1, 2026RSC AdvancesOpen Access

Derivatization-assisted dual-mode colorimetric and fluorometric detection of dopamine using 4-hexyl resorcinol

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Key Points

To establish a dual-mode sensing strategy for the detection of dopamine through derivatization methods.
Developed a derivatization-based sensing strategy using 4-hexyl resorcinol (4-HRS).
Employed oxidative coupling to produce azamonardine for detection.
Utilized both colorimetric and fluorescence techniques for sensitivity enhancement.
Achieved a highly emissive output with azamonardine for detection purposes.
Demonstrated increased sensitivity in both colorimetric and fluorescent detection methods.

Implication

Develops a dual-mode sensing strategy for dopamine detection, suggesting improved sensitivity.

Abstract

A derivatization-based dual-mode sensing strategy was developed for DA determination via oxidative coupling with 4-HRS, producing highly emissive azamonardine for sensitive colorimetric and fluorescence detection.

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Cite This Study

Goda et al. (2026) studied this question.

synapsesocial.com/papers/6a095b5d7880e6d24efe1172 https://doi.org/10.1039/d6ra02276f

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Derivatization-assisted dual-mode colorimetric and fluorometric detection of dopamine using 4-hexyl resorcinol

Key Points

Implication

Abstract

Discussion

Cite This Study

Derivatization-assisted dual-mode colorimetric and fluorometric detection of dopamine using 4-hexyl resorcinol

Key Points

Implication

Abstract

Discussion

Cite This Study

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