The impact of culturally tailored video interventions for Long COVID among Hispanic/Latino populations

Background: Long COVID has disproportionately affected Hispanic/Latino communities, particularly in Arizona. Structural inequities contribute to disparities, but limited culturally tailored health information remains an underexplored barrier to effective communication. This study evaluated the impact of culturally designed Long COVID educational videos for Hispanic/Latino audiences. Methods: We developed animated videos incorporating cultural symbols and diversity cues. Participants completed pre- and post-intervention surveys assessing Long COVID knowledge. Pre-post regression analyses examined knowledge gains, subgroup differences (education, gender, lived experience), and the influence of cultural design elements. Results: Baseline knowledge was higher among participants with greater educational attainment; however, post-intervention knowledge levels were similar across education groups. Female participants demonstrated lower scores than males, diverging from typical health information-seeking trends. Participants with lived experience of Long COVID reported higher baseline knowledge. Cultural design features, including symbolism and perceived diversity, showed modest effects, particularly among younger viewers. Overall, knowledge increased significantly following video exposure across all subgroups. Conclusions: Culturally tailored Long COVID videos effectively enhanced knowledge among Hispanic/Latino audiences, mitigating educational disparities and engaging individuals with diverse experiences. While cultural design elements had limited influence, they may enhance relevance for specific subgroups. These findings support the potential of culturally responsive video interventions to improve health education access in underserved communities and highlight areas for refinement in future multimedia health communication strategies.