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May 17, 2026Case Studies in Chemical and Environmental EngineeringOpen Access

Design and Optimization of 3D Printable Polyethylene Glycol Diacrylate (PEGDA)/Carboxy Methyl Cellulose (CMC) Hydrogels for Antibacterial Property Enhancement

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Authors

PPPaweena PattaraudomchokLTLih‐Sheng TurngMNManit Nititanakul

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Overview

Randomized trial reports effective antibacterial activity of PEGDA/CMC hydrogel patches with bioactive agents, indicating promising applications in healthcare.

Key Points

  • The aim is to design and optimize PEGDA/CMC hydrogels for enhanced antibacterial properties using black cumin seed oil as a bioactive agent.
  • Fabrication of hydrogel micropatterned patches using LCD 3D printing.
  • Application of Taguchi Design of Experiments to optimize printing parameters and geometries.
  • Evaluation of mechanical performance, swelling behavior, release kinetics, and antibacterial activity.
  • Conical micropatterns demonstrated the highest mechanical strength.
  • Controlled release of B-EO showed significant inhibition of Staphylococcus aureus.
  • Cytocompatibility assays confirm no cytotoxic effects on L929 fibroblasts.

Cite This Study

Pattaraudomchok et al. (2026) studied this question.

synapsesocial.com/papers/6a095bba7880e6d24efe1894https://doi.org/10.1016/j.cscee.2026.101407
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