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November 3, 2025CureusOpen Access

A Narrative Review of Tuberculosis and Diabetes Mellitus: The Double Burden Epidemiology, the Current Moment and the Future

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Authors

ESEmmanuel Sindato

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Overview

Narrative review reveals worsening clinical outcomes from overlapping tuberculosis and diabetes in low- and middle-income countries, highlighting the necessity of integrated care models.

Key Points

  • Summarize the epidemiology and negative synergism of the tuberculosis and diabetes double burden, and evaluate integrated care strategies to improve patient outcomes.
  • Searched PubMed, Embase, African Journals Online, and Google Scholar on January 1, 2025, for studies published between January 1, 2020, and December 1, 2024, without language restrictions.
  • Screened records against World Health Organization diagnostic and care integration guidelines, selecting 35 relevant articles for qualitative synthesis.
  • Identified an escalating double burden of tuberculosis and diabetes that disproportionately impacts low- and middle-income countries through negative disease synergism.
  • Demonstrated that integrated care models optimize patient outcomes by facilitating bi-directional screening and providing holistic disease management without overburdening fragile health systems.

Cite This Study

Emmanuel Sindato (2025) studied this question.

synapsesocial.com/papers/6a0978fd41a1eeaa064598cchttps://doi.org/10.7759/cureus.96016
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