Key result
Fast Fourier transform analysis of TTFM waveforms shows potential for intraoperative CABG quality assessment.
Why the study?
Determining clear-cut cutoff values for standard TTFM parameters to predict graft patency is difficult because they vary with hemodynamic characteristics such as target artery FFR.
Can fast Fourier transform analysis of intraoperative transit-time flow measurement waveforms be used for quality assessment of CABG grafts?
Can fast Fourier transform analysis of intraoperative transit-time flow measurement waveforms be used for quality assessment of CABG grafts?
FFT analysis of TTFM waveforms may provide additional value beyond standard parameters for assessing CABG graft patency intraoperatively.
May enhance intraoperative CABG graft assessment beyond standard TTFM; leaves open prospective validation before clinical adoption.
As the current guidelines on myocardial revascularization recommend, transit-time flow measurement (TTFM) is increasingly used for intraoperative graft flow analysis during coronary artery bypass grafting (CABG) as a less invasive, more highly reproducible, and less time-consuming method. In addition to the morphological assessment using color Doppler, mean graft flow (Qm) > 15 ml/min, pulsatility index (PI) < 5.0, diastolic filling (DF) > 50%, and systolic reverse flow (SRF) < 4% have been reported to predict patent CABG grafts. However, it is difficult to determine the clear-cut cut-off value of these parameters, because they varies with the hemodynamic characters, including fractional flow reserve (FFR) of the target coronary artery. In addition to these parameters, we focused on fast Fourier transform (FFT) analysis, because the TTFM waveform morphology may be more important than Qm itself. FFT analysis is based on the principle that any periodic waveforms can be broken down into a series of pure sine waves or harmonics. Herein we review FFT analysis of the intraoperative TTFM waveforms for quality assessment of CABG grafts.
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Takami et al. (2024) conducted a review in Coronary artery bypass grafting. Fast Fourier transform (FFT) analysis of transit-time flow measurement (TTFM) was evaluated. Fast Fourier transform analysis of intraoperative transit-time flow measurement waveforms is reviewed as a potential method for quality assessment of coronary artery bypass grafts.
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