What question did this study set out to answer?

Summarize recent insights into the enzymatic and molecular mechanisms mediating xylan degradation by Bacteroidetes species in the bovine rumen and human colon.

November 18, 2010Molecular Microbiology

Xylan degradation, a metabolic property shared by rumen and human colonic Bacteroidetes

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Authors

DDDylan DoddStanford Medicine RMRoderick I. MackieUniversity of Illinois Urbana-Champaign ICIsaac CannUniversity of Illinois Urbana-Champaign

Discussion

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Implication

Review highlights conserved molecular pathways of xylan breakdown in rumen and human Bacteroidetes, indicating common metabolic strategies impacting host nutrition and gut immunity.

Key Points

Summarize recent insights into the enzymatic and molecular mechanisms mediating xylan degradation by Bacteroidetes species in the bovine rumen and human colon.
Reviewed molecular and physiological evidence on lignocellulosic polysaccharide fermentation and short-chain fatty acid generation.
Compared the enzymatic machinery and metabolic adaptations of commensal Bacteroidetes across bovine rumen and human distal gut ecosystems.
Bacteroidetes constitute a core bacterial phylum responsible for digesting structural plant polysaccharides like xylan across both bovine and human hosts.
While ruminal xylan fermentation predominantly fulfills host energy demands, human colonic degradation alters microbiota composition and limits immune-mediated inflammation associated with inflammatory bowel diseases.

Cite This Study

Dodd et al. (2010) studied this question.

synapsesocial.com/papers/6a09f32716dfdfe7ed347f3c https://doi.org/10.1111/j.1365-2958.2010.07473.x

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November 18, 2010Molecular Microbiology

Xylan degradation, a metabolic property shared by rumen and human colonic Bacteroidetes

View Full Paper

Ask AI

Bookmark

Authors

DDDylan DoddStanford Medicine RMRoderick I. MackieUniversity of Illinois Urbana-Champaign ICIsaac CannUniversity of Illinois Urbana-Champaign

Discussion

Member takes

Implication

Review highlights conserved molecular pathways of xylan breakdown in rumen and human Bacteroidetes, indicating common metabolic strategies impacting host nutrition and gut immunity.

Key Points

Summarize recent insights into the enzymatic and molecular mechanisms mediating xylan degradation by Bacteroidetes species in the bovine rumen and human colon.
Reviewed molecular and physiological evidence on lignocellulosic polysaccharide fermentation and short-chain fatty acid generation.
Compared the enzymatic machinery and metabolic adaptations of commensal Bacteroidetes across bovine rumen and human distal gut ecosystems.
Bacteroidetes constitute a core bacterial phylum responsible for digesting structural plant polysaccharides like xylan across both bovine and human hosts.
While ruminal xylan fermentation predominantly fulfills host energy demands, human colonic degradation alters microbiota composition and limits immune-mediated inflammation associated with inflammatory bowel diseases.

Cite This Study

Dodd et al. (2010) studied this question.

synapsesocial.com/papers/6a09f32716dfdfe7ed347f3c https://doi.org/10.1111/j.1365-2958.2010.07473.x

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