What question did this study set out to answer?

To review published scientific literature and global patent collections to identify viable therapeutic agents, drug-repurposing candidates, and vaccines against SARS-CoV-2.

March 12, 2020ACS Central ScienceOpen Access

Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases

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To review published scientific literature and global patent collections to identify viable therapeutic agents, drug-repurposing candidates, and vaccines against SARS-CoV-2.
Extracted and categorized coronavirus-related scientific literature and patent data from the CAS content collection.
Assessed small-molecule candidates previously investigated for efficacy against RNA viruses, including SARS-CoV and MERS-CoV.
Profiled patent disclosures across four major classes of biologics: antibodies, cytokines, nucleic acid-based therapies, and vaccines.
Identified more than 500 patents detailing methodologies across the four biologic modalities with therapeutic or preventive potential against coronaviruses.
Mapped critical drug-repurposing targets that disrupt molecular pathways required for coronavirus infection and viral replication.

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Implication

Patent landscape analysis reveals extensive therapeutic and vaccine candidates against coronaviruses, highlighting viable drug-repurposing avenues for COVID-19.

Cite This Study

Liu et al. (2020) studied this question.

synapsesocial.com/papers/6a09f6b359b902245b464e76 https://doi.org/10.1021/acscentsci.0c00272

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Implication

Patent landscape analysis reveals extensive therapeutic and vaccine candidates against coronaviruses, highlighting viable drug-repurposing avenues for COVID-19.

Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases

Key Points

Discussion

Implication

Cite This Study

Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases

Key Points

Discussion

Implication

Cite This Study

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Also Consider