Key result
Preoperative institution of intra-aortic balloon counterpulsation significantly reduced in-hospital mortality compared to postoperative insertion (OR 0.13) in high-risk valve replacement patients.
Why the study?
The relationship between the timing of intra-aortic balloon counterpulsation (IABC) and surgical outcome in high-risk patients undergoing valve replacements remains debatable.
Does the timing of intra-aortic balloon counterpulsation (preoperative vs intraoperative vs postoperative) reduce in-hospital mortality in high-risk patients undergoing valve replacements for rheumatic heart disease?
Cohort (n=120)
No
Does the timing of intra-aortic balloon counterpulsation (preoperative vs intraoperative vs postoperative) reduce in-hospital mortality in high-risk patients undergoing valve replacements for rheumatic heart disease?
Effect estimate: OR 0.13 (95% CI 0.01-0.66)
Absolute Event Rate: 5.7% vs 32.4%
p-value: p=0.004
The relationship between the timing of intra-aortic balloon counterpulsation (IABC) and surgical outcome in high-risk patients undergoing valve replacements remain debatable. Perioperative IABC is commenced either prophylactically or after increasing inotropic support has proved inadequate. This study evaluates the effect timings of IABC support on the in-hospital mortality in patients undergoing valve replacements.
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Ujjwal K. Chowdhury (2019) conducted a cohort in Rheumatic Heart Disease (n=120). Preoperative intra-aortic balloon counterpulsation (IABC) vs. Postoperative IABC was evaluated on In-hospital mortality (OR 0.13, 95% CI 0.01-0.66, p=0.004). Preoperative institution of intra-aortic balloon counterpulsation significantly reduced in-hospital mortality compared to postoperative insertion (OR 0.13) in high-risk valve replacement patients.
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