Why the study?
It was unknown whether clinical outcomes from antihypertensive therapy vary by socioeconomic context in a randomized clinical trial with a standardized treatment protocol.
Does receiving care in lower-income sites worsen blood pressure control and cardiovascular outcomes in patients treated under a standardized antihypertensive protocol?
Population
27 862 qualifying ALLHAT participants
Comparison
Lowest-income sites (quintile 1) vs highest-income sites (quintile 5)
Design
Post hoc analysis of randomized clinical trial data
Authors
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Care at lower-income sites was associated with worse BP control and mortality despite protocols; leaves open whether targeted interventions can mitigate site-level disparities.
Does receiving care in lower-income sites worsen blood pressure control and cardiovascular outcomes in patients treated under a standardized antihypertensive protocol?
Despite standardized treatment protocols, patients treated at lower-income sites had worse blood pressure control and higher mortality, highlighting the impact of socioeconomic context on cardiovascular outcomes.
Shahu et al. (2019) studied this question.