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A case of a Wilms' tumor in a 67-year-old man is presented. The confusion in terminology and histology is discussed. It is often insufficiently appreciated that renal cell carcinoma is a structurally versatile neoplasm and may present a spindle cell or sarcomatous appearance in areas, and thus resemble a nephroblastoma. However, the pivotal histologic feature of a Wilms' tumor is the presence of immature glomerulotubular structures, and absence of this fetal renal tissue in an adult tumor indicates that it is probably an anaplastic renal cell carcinoma. Although from 79 to 133 cases of adult Wilms' tumor have been reported previously, many are poorly documented, and it is suggested that most are actually anaplastic renal cell carcinomas.
Olsen et al. (Thu,) studied this question.
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