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Summary A series of N-alkyl substituted derivatives of morphine has been synthesised and examined for analgesic and antianalgesic action. Several of these compounds have shown powerful antianalgesic activity, N-propylnormorphine and the diacetyl and dipropionyl derivatives of N-allylnormorphine (nalorphine) being about as active as nalorphine.
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GREEN et al. (1954) studied this question.
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