Key result
Depression, sleep apnea, daytime sleepiness, and ≥4 comorbidities are linked to poorer HF clinical status.
Why the study?
There was a gap in research regarding common factors that impact patients with advanced heart failure.
Observational (n=198)
Sleep apnea, daytime sleepiness, multiple comorbidities, and depression are significantly associated with poorer health status in patients with advanced systolic heart failure.
Answers are grounded in this paper and cite their sources.
These associations should not change practice; hypothesis-generating for interventions targeting depression and sleep in advanced HF.
There is a gap in current research on common factors that impact patients with advanced heart failure (HF). The purpose of this secondary data analysis was to explore associations of those factors with three empirically verified measures of HF-related clinical, physical, and mental health status. Baseline data of 198 advanced systolic HF (EF < 40%) patients were analyzed. Patients were 61.6% male, with a mean age of 62.3 ( SD = 13.2) years. The multivariable general linear modeling results indicated that patients who had poorer scores on HF-related clinical status were those who had sleep apnea ( β = −6.6, p < .05), daytime sleepiness ( β = −9.4, p < .01), four or more comorbidities ( β = −11.8, p < .001), and depression ( β = −18.7, p < .001). Depression was associated with all three measures of HF-related health status. These findings alert nurses to assess for sleep apnea and to use known screening measures for daytime sleepiness, depression, and comorbidities.
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Piamjariyakul et al. (2021) conducted an observational in Advanced systolic heart failure (n=198). Sleep apnea, daytime sleepiness, comorbidities, and depression was evaluated on HF-related clinical status (β -18.7, p=<.001). Depression (β=-18.7, p<0.001), sleep apnea (β=-6.6, p<0.05), daytime sleepiness (β=-9.4, p<0.01), and ≥4 comorbidities (β=-11.8, p<0.001) were associated with poorer HF-related clinical status.
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