Key result
Coronary microvascular dysfunction affects ~50% of CAD patients but lacks a single unifying mechanism.
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Design
Review
Heterogeneity in microvascular angina warrants cautious individualized strategies; leaves open mechanism-specific trials.
Nearly 50% of subjects of coronary artery disease suffer from coronary microvascular dysfunction. Various etiopathogenetic factors have been proposed by different workers but no hypothesis can explain the genesis of microvascular angina in all patients. We have made an attempt to review the literature to find caveats in our knowledge so that future studies can be better designed.
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S.R. Mittal (2014) studied this question. Coronary microvascular dysfunction affects nearly 50% of coronary artery disease patients, yet no single hypothesis currently explains the genesis of microvascular angina in all cases.
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