Key result
Distinct cell death pathways drive diabetic cardiomyopathy and represent novel therapeutic targets.
Why the study?
Cell death is considered the terminal pathway of cardiomyocytes in diabetic cardiomyopathy, making a synthesis of cell death mechanisms and implications beneficial to inform novel treatment strategies.
Design
Review
Authors
Loading...
Cell death pathways merit preclinical target validation in diabetic cardiomyopathy; leaves open clinical translation pending prospective trials.
This review outlines the distinct types of cell death involved in diabetic cardiomyopathy, highlighting potential molecular targets for future therapeutic strategies.
Chen et al. (2020) conducted a review in Diabetic cardiomyopathy. Distinct types of cell death, including apoptosis, autophagy, necrosis, and entosis, serve as terminal pathways in diabetic cardiomyopathy and represent potential targets for novel therapies.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: