What does this research mean for the field?

Focal atrial tachycardia originating from the distal left atrial appendage is an uncommon arrhythmia with distinct electrocardiographic features that can be safely and effectively treated with radiofrequency ablation, yielding high long-term success rates. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To characterize the electrocardiographic and electrophysiological properties and evaluate the long-term radiofrequency ablation outcomes of focal atrial tachycardia originating from the distal left atrial appendage.

September 20, 2011EP Europace

Focal atrial tachycardia originating from the distal portion of the left atrial appendage: characteristics and long-term outcomes of radiofrequency ablation

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Focal atrial tachycardia originating from the distal portion of the left atrial appendage (n=14). Intervention: Radiofrequency ablation. Primary outcome: Acute success.

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Key result

Radiofrequency ablation of focal atrial tachycardia originating from the distal left atrial appendage was acutely successful in 13 of 14 patients (92.9%), with no recurrences over 5 years.

Why the study?

Does radiofrequency ablation successfully treat focal atrial tachycardia originating from the distal left atrial appendage?

Population

14 patients with focal atrial tachycardia originating from the distal portion of the left atrial appendage…

Design

Case_series

Follow-up

5 ± 2 years

Authors

QYQin YangThird Affiliated Hospital of Southern Medical University JMJian MaElectrophysiology SZShu ZhangUniversity of Electronic Science and Technology of China

Discussion

Member takes

Implication

Supports RFA consideration for refractory distal LAA AT; leaves open confirmation in prospective series.

Key Points

To characterize the electrocardiographic and electrophysiological properties and evaluate the long-term radiofrequency ablation outcomes of focal atrial tachycardia originating from the distal left atrial appendage.
Identified 14 patients (mean age 25 ± 10 years; 9 females; mean symptom duration 5 ± 5 years) with focal atrial tachycardia arising from the distal left atrial appendage out of 668 patients undergoing radiofrequency ablation.
Performed electrophysiological activation mapping, categorized P-wave morphology across standard leads, and administered radiofrequency ablation with a mean follow-up of 5 ± 2 years.
All patients experienced incessant tachycardia characterized by negative P waves in leads I and aVL, positive inferior leads, broad positive V₁, and an endocardial activation time 47.1 ± 4.3 ms prior to P-wave onset.
Acute radiofrequency ablation success occurred in 13 of 14 patients (92.9%) with zero procedural complications.
Long-term success without recurrence was maintained in 13 of 13 successfully ablated patients (100%) throughout the 5 ± 2 years of follow-up.

Study Design

Type

Observational (n=14)

Structured PICO

Does radiofrequency ablation successfully treat focal atrial tachycardia originating from the distal left atrial appendage?

Population

14 patients with focal atrial tachycardia (AT) originating from the distal portion of the left atrial appendage (LAAd), mean age 25 ± 10 years, 9 women, mean symptom duration 5 ± 5 years.

Intervention

Radiofrequency ablation (RFA)

Outcome

Acute success rate and long-term success during follow-up

Radiofrequency ablation is a highly effective and safe treatment for the rare focal atrial tachycardia originating from the distal left atrial appendage.

Cite This Study

Yang et al. (2011) conducted an observational in Focal atrial tachycardia originating from the distal portion of the left atrial appendage (n=14). Radiofrequency ablation was evaluated on Acute success. Radiofrequency ablation of focal atrial tachycardia originating from the distal left atrial appendage was acutely successful in 13 of 14 patients (92.9%), with no recurrences over 5 years.

synapsesocial.com/papers/6a0a58e4fdd00ab7863dcd96 https://doi.org/10.1093/europace/eur302

Topics

Atrial fibrillation Persistent AF management Left atrial appendage closure AF ablation outcomes

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Focal atrial tachycardia originating from the distal portion of the left atrial appendage: characteristics and long-term outcomes of radiofrequency ablation

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Focal atrial tachycardia originating from the distal portion of the left atrial appendage: characteristics and long-term outcomes of radiofrequency ablation

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

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