Key result
Right ventricular endomyocardial biopsy confirmed pathologic small coronary arteries in 6 patients with classic angina pectoris and patent large coronary arteries.
Why the study?
Can small-vessel coronary artery disease cause classic angina pectoris in patients with patent large coronary arteries?
Population
6 patients with angina pectoris and angiographically patent major coronary arteries
Comparison
Diagnostic evaluation including coronary… vs Control group
Design
Case_series
Authors
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Biopsy may identify small-vessel disease causing angina with normal large arteries; hypothesis-generating and should not yet change practice.
Observational (n=6)
Can small-vessel coronary artery disease cause classic angina pectoris in patients with patent large coronary arteries?
Small-vessel coronary artery disease can cause classic angina pectoris in patients with patent large coronary arteries, which can be suspected by slow angiographic flow and confirmed by endomyocardial biopsy.
Mosseri et al. (1986) conducted an observational in Angina pectoris with patent large coronary arteries (n=6). Right ventricular endomyocardial biopsy and coronary angiography vs. Control group was evaluated on Histologic evidence of small-vessel coronary artery disease and angiographic flow velocity. Right ventricular endomyocardial biopsy confirmed pathologic small coronary arteries in 6 patients with classic angina pectoris and patent large coronary arteries.
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