Why the study?
Cardiac rupture is a catastrophic complication of STEMI, but its incidence and risk factors remain unclear in the contemporary era.
Observational (n=416)
No
Female sex and older age are significant risk factors for cardiac rupture complicating STEMI, whereas primary PCI is protective.
Identifies high-risk STEMI subgroups for cardiac rupture; hypothesis-generating and should not yet change practice.
Objective: Cardiac rupture is a catastrophic but uncommon complication of acute ST-segment elevation myocardial infarction (STEMI). In today's era, the incidence and risk factors associated with cardiac rupture are unclear, and the purpose of this study was to investigate the risk factors for complications of cardiac rupture. Methods: From June 2019 to June 2022, 416 patients with STEMI admitted From June 9 to June 2022, 416 patients with STEMI admitted to the Department of Cardiovascular Medicine of the First People's Hospital of Jingzhou City were selected, and the clinical characteristics of patients with STEMI and patients with concomitant cardiac rupture were collected and analyzed. Results: Twenty-six (6.3%) cardiac ruptures were clinically confirmed, including 23 (6.3%) cardiac ruptures in patients with STEMI and patients with concomitant cardiac rupture. clinically confirmed, including 23 (88.5%) left ventricular free wall ruptures and 3 (11.5%) ventricular septal ruptures, of which 14 (53.8%) were Binary logistic regression analysis showed that women (OR:4.82, 95% CI: 2.143 to 10.843, P=0) and older age (OR:1.066, 95% CI: 1.014 to 1.121, P=0.012) increased the risk of cardiac rupture, while effective pPCI (OR:0.146, 95% CI: 0.057 to 0.379, P=0) helped prevent cardiac Smoking (OR:0.092, 95% CI: 0.021 to 0.403, P=0.002) appeared to reduce the risk of cardiac rupture complicated by STEMI. Conclusion: In this study women, old age, and low pPCI reperfusion therapy increased the risk of cardiac rupture complicating STEMI, so early prevention and treatment should be achieved.
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Hao Chen (2022) conducted an observational in Acute ST-segment Elevation Myocardial Infarction (STEMI) (n=416). Risk factor analysis was evaluated on Cardiac rupture (associated with female sex) (OR 4.82, 95% CI 2.143-10.843, p=0.000).
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