Key result
The choice between bileaflet and monoleaflet mechanical prosthetic valves did not significantly affect the improvement in left ventricular ejection fraction (60.35% vs 61.23%, p=0.341) one year after aortic valve replacement.
Why the study?
It was unknown whether the choice of mechanical prosthetic valve (bileaflet or monoleaflet) affects changes in left ventricular functions and valve gradients after aortic valve replacement in patients with pure aortic valve disease.
Does the choice of mechanical prosthetic valve (bileaflet vs monoleaflet) affect change in left ventricular functions after aortic valve replacement in patients with pure aortic valve disease?
Cohort (n=82)
No
Does the choice of mechanical prosthetic valve (bileaflet vs monoleaflet) affect change in left ventricular functions after aortic valve replacement in patients with pure aortic valve disease?
The choice between bileaflet and monoleaflet mechanical prosthetic valves for aortic valve replacement does not significantly influence the postoperative improvement in left ventricular function.
Background: We sought to determine whether the choice of mechanical prosthetic valve (Bileaflet or Monoleaflet) has any effect on change in left ventricular functions and valve gradients after aortic valve replacement (AVR) in patients with pure aortic valve disease. Methods: Eighty two patients were included in the study who underwent aortic valve replacement for isolated aortic valve disease using either a bileaflet (Group1) or a monoleaflet valve (Group 2). The measurements included Left Ventricular End-Diastolic (LVEDd) and Left Ventricular End-Systolic (LVEDs) dimensions and Left Ventricular End-Diastolic (LVEDV) and Left Ventricular End-Systolic (LVESV) volumes, Ejection Fraction (EF), Stroke Volume (SV), NYHA class and Cardiac Output (CO). Comparisons of different parameters were made in two groups to determine the significance of choice of prosthetic valve. Results: Aortic valve replacement induces a favourable remodeling of the left ventricle and a significant improvement in left ventricular functions. There was no statistically significant difference in the measured parameters between the two groups and hence choice of prosthetic valve does not influence the outcome. Conclusion: Impaired cardiac functions show significant improvement after AVR. Functional class was improved or maintained in all the patients in both the groups. Left ventricular systolic pump functions were improved in almost all the patients, comparable in both the groups.
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Hakeem Zubair Ashraf (2020) conducted a cohort in Isolated aortic valve disease (n=82). Bileaflet mechanical prosthetic valve vs. Monoleaflet mechanical prosthetic valve was evaluated on Postoperative Ejection Fraction (%) (p=0.341). The choice between bileaflet and monoleaflet mechanical prosthetic valves did not significantly affect the improvement in left ventricular ejection fraction (60.35% vs 61.23%, p=0.341) one year after aortic valve replacement.
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