What question did this study set out to answer?

To develop and experimentally evaluate an improved NMR diffusion coefficient imaging method with an optimized pulse sequence designed to maximize signal-to-noise ratio.

November 1, 1986Medical Physics

An improved nuclear magnetic resonance diffusion coefficient imaging method using an optimized pulse sequence

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Authors

CAC.B. AhnKwangwoon University SLS. Y. LeeUniversity of California, Irvine ONO. NalcioǧluKorea Institute for Advanced Study

Discussion

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Implication

Experimental imaging study demonstrates improved diffusion coefficient mapping using an optimized pulse sequence in phantoms and human volunteers, indicating enhanced signal-to-noise ratio.

Key Points

To develop and experimentally evaluate an improved NMR diffusion coefficient imaging method with an optimized pulse sequence designed to maximize signal-to-noise ratio.
Acquired 2D diffusion coefficient maps using a novel sequence on a 0.6-T whole-body NMR scanner with a 2.5 mT/m gradient field strength by varying readout gradient duration in 2D Fourier imaging.
Calculated and experimentally verified the optimal spin-echo time for maximal SNR in a controlled diffusion phantom, followed by preclinical validation in human volunteers.
Diffusion coefficient measurements obtained from the phantom demonstrated close agreement with previously established benchmark values.
Optimal spin-echo time selection successfully maximized SNR, enabling effective preclinical diffusion imaging in human subjects.

Cite This Study

Ahn et al. (1986) studied this question.

synapsesocial.com/papers/6a0a9378286b3ba5d970a596 https://doi.org/10.1118/1.595850

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November 1, 1986Medical Physics

An improved nuclear magnetic resonance diffusion coefficient imaging method using an optimized pulse sequence

View Full Paper

Ask AI

Bookmark

Authors

CAC.B. AhnKwangwoon University SLS. Y. LeeUniversity of California, Irvine ONO. NalcioǧluKorea Institute for Advanced Study

Discussion

Member takes

Implication

Experimental imaging study demonstrates improved diffusion coefficient mapping using an optimized pulse sequence in phantoms and human volunteers, indicating enhanced signal-to-noise ratio.

Key Points

To develop and experimentally evaluate an improved NMR diffusion coefficient imaging method with an optimized pulse sequence designed to maximize signal-to-noise ratio.
Acquired 2D diffusion coefficient maps using a novel sequence on a 0.6-T whole-body NMR scanner with a 2.5 mT/m gradient field strength by varying readout gradient duration in 2D Fourier imaging.
Calculated and experimentally verified the optimal spin-echo time for maximal SNR in a controlled diffusion phantom, followed by preclinical validation in human volunteers.
Diffusion coefficient measurements obtained from the phantom demonstrated close agreement with previously established benchmark values.
Optimal spin-echo time selection successfully maximized SNR, enabling effective preclinical diffusion imaging in human subjects.

Cite This Study

Ahn et al. (1986) studied this question.

synapsesocial.com/papers/6a0a9378286b3ba5d970a596 https://doi.org/10.1118/1.595850

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