What question did this study set out to answer?

The study aims to explore the relationship between socioeconomic status and survival rates for sepsis in ICU admissions in Australia.

May 18, 2026Australian Critical Care1 citationsOpen Access

Socioeconomic disadvantage and sepsis survival in Australian intensive care units: A retrospective cohort study

KTKelly ThompsonThe George Institute for Global Health KHKimberley HainesThe University of Melbourne ACAnis ChabaAustin Hospital

Key Points

The study aims to explore the relationship between socioeconomic status and survival rates for sepsis in ICU admissions in Australia.
Conducted a retrospective cohort study of sepsis ICU admissions from 2018 to 2023
Used Cox proportional hazard models to analyze the relationship between socioeconomic status and survival after adjusting for various factors
Analyzed data from 794,756 admissions, focusing on 80,422 sepsis cases.
180-day mortality was 24.0% for low socioeconomic status (SES) compared to 22.9% for middle SES and 23.0% for high SES
In-hospital 30-day mortality rates were 14.7% for low SES, 13.7% for middle SES, and 14.1% for high SES
High SES patients had significantly better survival outcomes, with adjusted hazard ratios of 0.86 (180-day) and 0.88 (30-day), both p < 0.001.

Abstract

OBJECTIVE: The aim of this study was to investigate the association between socioeconomic status (SES) and sepsis survival in Australian intensive care unit (ICU) admissions. METHODS: We conducted a retrospective cohort study of adult sepsis ICU admissions between 2018 and 2023, using ICU registry and national death data. SES was derived using the Australian Bureau of Statistics Index of Relative Socioeconomic Advantage and Disadvantage deciles mapped from residential postcodes and categorised as low, middle, or high. Unadjusted survival to 180 days and in-hospital 30-day survival were described using Kaplan-Meier estimates. Cox proportional hazard models, adjusted for age, sex, organ failure, ICU admission source, elective surgical status, chronic conditions, admission year, study site, and the presence of septic shock, were used to determine associations between SES and survival. RESULTS: Of 794,756 admissions, 80,422 (10.1%) were sepsis admissions; 180-day mortality was 7570 of 31,528 (24·0%) in low SES admissions compared to 5109 of 22262 (22.9%) and 6009 of 26,088 (23·0%) in middle and high SES admissions, respectively. In-hospital 30-day mortality was 4662 of 31,613 (14·7%) in low SES admissions compared to 3079 of 22348 (13.7%) and 3695 of 26,221 (14·1%) in middle and high SES admissions, respectively. In adjusted Cox regression models, high SES was associated with greater 180-day and in-hospital 30-day survival (adjusted hazard ratio: 0·86, 95% confidence interval: 0·83-0·90; p < 0·001 and adjusted hazard ratio: 0·88, 95% confidence interval: 0·84-0·93; p < 0·001, respectively). CONCLUSION: People living in areas of socioeconomic disadvantage had lower survival to day 180 after an ICU admission for sepsis than people living in other areas.

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Cite This Study

Thompson et al. (Fri,) studied this question.

synapsesocial.com/papers/6a0aac2b5ba8ef6d83b6fabe https://doi.org/https://doi.org/10.1016/j.aucc.2026.101604

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