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May 18, 2026Internal MedicineOpen Access

A Case of Enteric-Type Thymic Adenocarcinoma Treated with Lenvatinib

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Authors

YHYasushi HosokawaTSTomoaki SonodaMAMasaki Anzai

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Overview

Case report highlights lenvatinib’s limited effectiveness for recurrent enteric-type thymic adenocarcinoma with brain metastases.

Key Points

  • Explore treatment options for stage IVB enteric-type thymic adenocarcinoma using lenvatinib.
  • Case report of a 56-year-old woman with stage IVB enteric-type thymic adenocarcinoma
  • Treated with chemoradiotherapy and subsequent lenvatinib
  • Monitored for response to treatment and progression of the disease
  • Low-dose lenvatinib led to a reduction in the size of recurrent lesions
  • Patient developed new brain metastases and carcinomatous meningitis 5 months after treatment
  • Patient ultimately succumbed to cancer, indicating possible limitations of lenvatinib in advanced stages

Cite This Study

Hosokawa et al. (2026) studied this question.

synapsesocial.com/papers/6a0aac2b5ba8ef6d83b6fc40https://doi.org/10.2169/internalmedicine.7104-26
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