Abstract Chordoma is a rare, slow-growing malignant tumor of notochordal origin, accounting for 1%–4% of primary skeletal neoplasms, most commonly in the sacrococcygeal region. We report a 44-year-old male with dull, progressive sacrococcygeal pain and numbness for 6 months. Imaging showed a lytic, metabolically active sacral–coccygeal lesion, and surgical excision yielded a 6 cm × 5 cm × 3.5 cm gelatinous mass. Histology revealed physaliferous cells in a lobulated, myxoid background, confirming conventional chordoma, with brachyury positivity. The tumor involved the posterior margin. Given their aggressive, recurrent nature, chordomas require complete excision, radiotherapy, and multidisciplinary evaluation for optimal outcomes.
Kulkarni et al. (Thu,) studied this question.