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May 18, 2026Journal of Engineering and Science in Medical Diagnostics and Therapy0 citations

Effect of moderate Stenosis on the upstream and downstream flow patterns in the Internal Carotid artery- An Invitro Investigation

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GKG KumarKTK. C. TripathyABAjay Bhandari

Key Points

  • This study aims to investigate how moderate stenosis affects flow patterns in the internal carotid artery, particularly near an aneurysm.
  • In vitro simulation using a blood-mimicking fluid to replicate physiological conditions
  • Flow visualization utilizing Particle Streak Velocimetry for detailed velocity field capture
  • Assessment of axial and transverse velocity components to analyze secondary flow behavior
  • Axial velocity profile in stenosed conditions became smoother and more parabolic compared to non-stenotic cases
  • Transverse velocity plots indicate clear flow disturbances and recirculation zones downstream of the stenosis
  • Findings highlight potential clinical implications of altered flow structure in stenosed arteries

Abstract

Abstract Narrowing of the internal carotid artery (ICA), known as stenosis, can significantly alter normal blood flow and increase the likelihood of cerebrovascular complications such as ischemic stroke. This study presents an in vitro investigation of flow dynamics within a stenosed ICA with an aneurysm at the carotid ophthalmic junction. A blood-mimicking fluid was circulated through the model, allowing for flow behavior similar to physiological conditions. Flow visualization was achieved using Particle Streak Velocimetry (PSV), a non-invasive optical measurement technique capable of capturing the detailed velocity fields. The axial velocity revealed an interesting phenomenon: the velocity profile became smoother and tended towards a more parabolic shape compared to the non-stenotic case, where the peak typically shifts toward the inner curvature region. However, this asymmetry became less pronounced within the stenotic section. The presence of stenosis introduces an equivalent opposing curvature, which effectively neutralizes the asymmetric flow distribution. Furthermore, the transverse velocity component (v) was plotted along the axial direction (x) to assess secondary flow behavior. The resulting v versus x plot exhibited clear indications of flow disturbances and recirculation zones downstream of the constriction. These findings demonstrate how stenosis modifies the flow structure within the artery, potentially contributing to adverse clinical outcomes. The experimental approach using a blood-mimicking fluid and PSV enables a detailed understanding of hemodynamic behavior in stenosed arteries. Such insights are valuable for advancing diagnostic methods and improving treatment planning in vascular diseases.

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Cite This Study

Kumar et al. (2026) studied this question.

synapsesocial.com/papers/6a0aaccf5ba8ef6d83b7030ehttps://doi.org/10.1115/1.4071950
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