• Foundation models are redefining crop disease detection and management. • VLM adoption surged 5–10 × over LLMs between 2023 and 2024. • Reinforcement learning for autonomous smart spraying remains nascent. • Digital twins coupled with RL bridge the sim-to-real gap in smart spraying. • Human-robot collaboration in field-scale disease management is underexplored. Site-specific disease management (SSDM) in agricultural crops has witnessed tremendous advancements over the past few decades using conventional machine and deep learning (ML & DL) approaches for real-time computer vision applications. This research has evolved from handcrafted feature extraction to large-scale automated feature learning in single-modality datasets. However, with the rise of foundation models (FMs), the way large-scale crop disease datasets are processed is being fundamentally transformed. Unlike convolutional neural networks (CNNs), which are inherently single-modality architectures and require post-fusion strategies to integrate heterogenous data streams, vision-language FMs provide unified embedding spaces where visual and textual representations are jointly learned from the same training dataset. This enables richer, more coherent cross-modal reasoning, allowing models to interpret disease symptoms described in text, infer relationships between symptoms and management factors, and support interactive Q&A platforms for growers and extension educators. Beyond visual and textual reasoning, FMs are also serving as backbone architectures for robotic perception and decision-making, bridging the gap between scene understanding and physical action in field environments. In this context, the integration of adaptive, imitation, and reinforcement learning (AL, IL, & RL) in robotics is enabling novel applications for field-based disease management. Therefore, this study reviewed ≈40 research articles to highlight the application of FMs for SSDM in crops, focusing on two primary themes: large-language models (LLMs), and vision language models (VLMs). Additionally, the extended role of FMs in enabling AL, IL, RL, and digital twin (DT) frameworks for robotics-based targeted spraying is also discussed. Based on the results and discussion, several key conclusions emerge from this review: (a) FMs are gaining traction, with a notable increase in reported technical literature during 2023-2024, (b) VLMs are being leveraged more than LLMs, with a five-to-tenfold increase in published articles from 2023 to 2024, (c) RL and AL remain in their infancy for developing smart spraying technologies that learn from experience, (d) integrating DTs with RL in cyber-physical systems offer a transformative approach for simulating targeted spraying in virtual environments, (e) addressing sim-to-real gap, the performance drop when models trained in simulated environments are deployed in real-world disease scenarios, will be critical for robust and scalable management systems, (f) while perception models for disease detection are advancing, human-robot collaboration and human-in-the-loop (HiTL) approaches remain underexplored in field-scale crop disease management systems where robots autonomously detect early symptoms and humans validate uncertain cases, and (g) continued advancements in FMs. Multi-modal integration, and real-time feedback are expected to drive the next generation of SSDM technologies.
Rai et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: