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May 18, 2026CureusOpen Access

A Case of Advanced Charcot-Marie-Tooth Disease Showing Extreme Lumbosacral Nerve Root Hypertrophy

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Authors

JLJohn Paul LemchakLake Erie College of Osteopathic MedicineJBJustin Brown-GnarraLake Erie College of Osteopathic MedicineCRChristian RobertiLake Erie College of Osteopathic Medicine

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Implication

Case report reveals severe nerve root hypertrophy in a 43-year-old man with Charcot-Marie-Tooth Disease, suggesting imaging's role in diagnosis.

Key Points

  • To highlight the features of advanced Charcot-Marie-Tooth disease through imaging findings.
  • Case report of a 43-year-old man with advanced Charcot-Marie-Tooth disease.
  • Neurological examination and nerve conduction studies were performed.
  • MRI and myelography were used to assess nerve root anatomy.
  • MRI showed diffuse, symmetric hypertrophy of lumbosacral nerve roots.
  • Nerve conduction studies indicated severely reduced sural nerve conduction velocity.
  • Imaging findings supported the diagnosis of hypertrophic demyelinating neuropathy.

Cite This Study

Lemchak et al. (2026) studied this question.

synapsesocial.com/papers/6a0aad2a5ba8ef6d83b70aa7https://doi.org/10.7759/cureus.108971
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