Key result
Diabetes was associated with significantly higher hospital mortality in patients admitted with acute myocardial infarction compared to nondiabetic patients (42.2% vs 24.7%; OR 2.22; 95% CI 1.37-3.60).
Why the study?
Does diabetes mellitus increase hospital mortality and admission risk in patients with myocardial infarction, and is this risk related to prior glycemic control?
Population
83 diabetic patients admitted with acute myocardial infarction, 380 nondiabetic patients with acute…
Comparison
Diabetes mellitus (exposure) vs Nondiabetic patients and diabetic patients…
Design
Cohort
Follow-up
Hospital stay
Authors
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Diabetes may confer higher AMI mortality; leaves open whether glycemic control modifies this observational association.
Observational (n=712)
Does diabetes mellitus increase hospital mortality and admission risk in patients with myocardial infarction, and is this risk related to prior glycemic control?
Effect estimate: OR 2.22 (95% CI 1.37-3.60)
Absolute Event Rate: 42.2% vs 24.7%
p-value: p=<0.002
Diabetes significantly increases hospital mortality in patients with acute myocardial infarction, primarily due to pump failure, but this risk is not associated with prior cumulative glycemic exposure.
Yudkin et al. (1988) conducted an observational in Acute myocardial infarction and diabetes (n=712). Diabetes mellitus vs. Nondiabetic patients was evaluated on Hospital mortality (OR 2.22, 95% CI 1.37-3.60, p=<0.002). Diabetes was associated with significantly higher hospital mortality in patients admitted with acute myocardial infarction compared to nondiabetic patients (42.2% vs 24.7%; OR 2.22; 95% CI 1.37-3.60).
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