Key result
Review traces Japanese atherosclerotic risk research and compares cardiovascular risk tools with Western models.
This review highlights the need to validate Western cardiovascular risk scores in Japanese populations and discusses risk factors and assessment tools specific to clinical practice in Japan.
Answers are grounded in this paper and cite their sources.
May support Japan-specific risk tools in practice; leaves open prospective validation of Western scores in Japanese populations.
Increased global mortality is associated with atherosclerosis, which appears to be independent of race. Cardiovascular disease is one of the leading causes of mortality and morbidity in Japan. Atherosclerosis, an inflammatory disease characterized by abnormal lipid accumulation and inflammation in the arterial wall, is the main underlying cause of cardiovascular disease. Numerous cardiovascular risk scores have been developed and are used to prioritize patients' treatment needs. The predictive performance of risk scores established in Western nations needs to be examined in Japanese populations. For secondary prevention, it is imperative to control hypertension, hyperlipidemia, diabetes mellitus, smoking, and local interventions. In this review, we present a historical overview of atherosclerotic risk research and the risk factors for atherosclerosis in Japan and compare the situation in Japan with that in Western nations. In addition, we discuss relevant cardiovascular risk assessment tools in the context of clinical practice in Japan.
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Nojiri et al. (2017) conducted a review in Atherosclerosis. This review provides a historical overview of atherosclerotic risk research and risk factors in Japan, and discusses relevant cardiovascular risk assessment tools compared to Western nations.
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