Key result
Obesity in critically ill patients was not associated with increased ICU mortality (RR 1.00; 95% CI 0.86-1.16; p=0.97) but significantly prolonged mechanical ventilation and ICU length of stay.
Why the study?
Does obesity affect intensive care unit mortality, duration of mechanical ventilation, and length of stay in critically ill patients?
Meta-Analysis (n=62,045)
Does obesity affect intensive care unit mortality, duration of mechanical ventilation, and length of stay in critically ill patients?
In critically ill patients, obesity does not increase ICU mortality but is associated with prolonged mechanical ventilation and ICU length of stay, with a potential survival benefit in those with BMI 30-39.9 kg/m2.
Answers are grounded in this paper and cite their sources.
Obesity should not drive ICU mortality risk stratification; confirms obesity paradox while extending evidence for prolonged ventilation and stay.
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Akinnusi et al. (2008) conducted a meta-analysis in Critically ill medical and surgical patients (n=62,045). Obesity (BMI ≥ 30 kg/m2) vs. Nonobese (BMI < 30 kg/m2) was evaluated on Intensive care unit mortality (RR 1.00, 95% CI 0.86-1.16, p=0.97). Obesity in critically ill patients was not associated with increased ICU mortality (RR 1.00; 95% CI 0.86-1.16; p=0.97) but significantly prolonged mechanical ventilation and ICU length of stay.
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