Key result
Self-supervised pre-training outperforms existing approaches for ECG classification with 0.945 AUC.
Why the study?
Automating ECG interpretation via machine learning is hindered by the difficulty and expense of collecting large annotated datasets, making effective self-supervised pre-training methods needed.
Self-supervised pre-training using JEPA significantly improves ECG classification performance compared to existing methods.
May advance automated ECG interpretation; leaves open prospective clinical validation.
Accurate diagnosis of heart arrhythmias requires the interpretation of electrocardiograms (ECG), which capture the electrical activity of the heart. Automating this process through machine learning is challenging due to the need for large annotated datasets, which are difficult and costly to collect. To address this issue, transfer learning is often employed, where models are pre-trained on large datasets and fine-tuned for specific ECG classification tasks with limited labeled data. Self-supervised learning has become a widely adopted pre-training method, enabling models to learn meaningful representations from unlabeled datasets. In this work, we explore the joint-embedding predictive architecture (JEPA) for self-supervised learning from ECG data. Unlike invariance-based methods, JEPA does not rely on hand-crafted data augmentations, and unlike generative methods, it predicts latent features rather than reconstructing input data. We create a large unsupervised pre-training dataset by combining ten public ECG databases, amounting to over one million records. We pre-train Vision Transformers using JEPA on this dataset and fine-tune them on various PTB-XL benchmarks. Our results show that JEPA outperforms existing invariance-based and generative approaches, achieving an AUC of 0.945 on the PTB-XL all statements task. JEPA consistently learns the highest quality representations, as demonstrated in frozen evaluations, and proves advantageous for pre-training even in the absence of additional data.
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Weimann et al. (2025) studied Heart arrhythmias (n=1,000,000). Joint-embedding predictive architecture (JEPA) vs. Invariance-based and generative approaches was evaluated on AUC on the PTB-XL all statements task. Self-supervised pre-training using the joint-embedding predictive architecture outperformed existing approaches for ECG classification, achieving an AUC of 0.945 on the PTB-XL benchmark.
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