Key result
4D MR velocity mapping showed blood transit time from the aortic valve to mid-descending aorta increased from <1 heartbeat in young subjects to 3 heartbeats in subjects >78 years.
Why the study?
How do blood flow patterns in the thoracic aorta, assessed by 4D magnetic resonance velocity mapping, differ between young and elderly normal subjects?
Population
16 normal subjects, comprising a young group and an elderly group.
Comparison
4D magnetic resonance velocity mapping using… vs Young vs. elderly subjects
Design
Cross-sectional
Authors
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Requires age-adjusted 4D flow norms before clinical use; leaves open outcome prediction in elderly.
Observational (n=16)
How do blood flow patterns in the thoracic aorta, assessed by 4D magnetic resonance velocity mapping, differ between young and elderly normal subjects?
4D MR velocity mapping demonstrates significant age-related changes in aortic blood flow patterns, including increased transit time and altered velocity profiles in elderly subjects.
Bogren et al. (1999) conducted an observational in Healthy subjects (n=16). 4D magnetic resonance velocity mapping vs. Young vs. elderly subjects was evaluated on Blood flow patterns and transit time in the thoracic aorta. 4D MR velocity mapping showed blood transit time from the aortic valve to mid-descending aorta increased from <1 heartbeat in young subjects to 3 heartbeats in subjects >78 years.
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