Key result
Digital healthcare management linked to ~42% lower all-cause mortality vs conventional care in CAD patients.
Why the study?
Post-discharge management of coronary artery disease remains clinically challenging, and the efficacy of digital healthcare is underexplored.
Does digital management reduce mortality and cardiovascular events in discharged patients with coronary artery disease?
Cohort (n=16,797)
Does digital management reduce mortality and cardiovascular events in discharged patients with coronary artery disease?
Effect estimate: HR 0.58 (95% CI 0.45-0.75)
Absolute Event Rate: 1.6% vs 2.7%
p-value: p=<0.001
Digital healthcare management for discharged CAD patients significantly reduces mortality and cardiovascular morbidity compared to conventional care.
May support digital post-discharge CAD care; leaves open causal effects and adoption pending RCTs.
Post-discharge management of coronary artery disease (CAD) remains clinically challenging, with digital healthcare's efficacy underexplored. This study analyzed 16,797 CAD patients enrolled in the HeartMed Digital Management System (June 2018-September 2022), comparing outcomes between a digital management (DM, n = 4,713) and conventional management (CM, n = 12,084) cohort over 12 months. Cox models adjusted for confounders revealed significantly reduced all-cause mortality in the DM group (1.6% vs. 2.7%; HR 0.58, 95% CI 0.45-0.75, p < 0.001) and lower risks for major adverse cardiovascular events (MACCE: 6.4% vs. 9.2%; HR 0.67, 0.59-0.77, p < 0.001), cardiovascular death (HR 0.70, 0.51-0.95), myocardial infarction (HR 0.38, 0.29-0.50), recurrent angina (HR 0.75, 0.65-0.87), revascularization (HR 0.84, 0.71-0.99), and readmissions (HR 0.76, 0.68-0.84) (p < 0.05 for all). Digital healthcare demonstrates superior post-discharge optimization of CAD outcomes, significantly attenuating mortality and morbidity.
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Yang et al. (2025) conducted a cohort in Coronary artery disease (n=16,797). Digital management (HeartMed Digital Management System) vs. Conventional management was evaluated on All-cause mortality (HR 0.58, 95% CI 0.45-0.75, p=<0.001). Digital healthcare management significantly reduced all-cause mortality (HR 0.58) compared to conventional management in discharged patients with coronary artery disease over 12 months.
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