Key result
Left atrial diameter negatively correlates with LVEF and differs between HFpEF and HFrEF.
Why the study?
Left atrial enlargement predicts cardiovascular adverse events, but the relationship between left atrial diameter and HFpEF, HFrEF, and HFmrEF remains unclear.
Is left atrial diameter correlated with left ventricular ejection fraction and heart failure subtypes in hospitalized patients?
Observational (n=210)
No
Is left atrial diameter correlated with left ventricular ejection fraction and heart failure subtypes in hospitalized patients?
Left atrial diameter is negatively correlated with left ventricular ejection fraction and may help differentiate between heart failure subtypes.
BACKGROUND: In patients with heart failure, left atrial remodeling often occurs to varying degrees. Left atrial enlargement has been proved to be an important predictor of cardiovascular-related adverse events. However, the relationship between left atrial diameter (LAD) with heart failure (HF) with preserved ejection fraction (HFpEF), reduced ejection fraction (HFrEF) and mid-range ejection fraction (HFmrEF) remains unclear. HYPOTHESIS: We want to explore the correlation between left atrial diameter and HFpEF, HFmrEF, and HFrEF. METHODS: A total of 210 patients with heart failure who underwent hospitalization in Ningbo Medical Center Lihuili Hospital, Zhejiang, China, from January 1, 2020, to June 31, 2021, were reviewed. The basic demographic characteristics, blood test, and the related indexes of echocardiography of the subjects were collected and analyzed. RESULTS: There is a significant difference between HFpEF and HFrEF group in LAD (p = .007), and LAD is negatively correlated with left ventricular ejection fraction (LVEF) (p = .002, r = -.209). CONCLUSION: LAD is negatively correlated with LVEF, which may predict the prevalence of HFrEF.
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Lin et al. (2023) conducted an observational in Heart failure (n=210). Left atrial diameter (LAD) was evaluated on Correlation between left atrial diameter and left ventricular ejection fraction (r = -0.209, p=0.002). Left atrial diameter is negatively correlated with left ventricular ejection fraction (r = -0.209, p = 0.002) and differs significantly between HFpEF and HFrEF groups (p = 0.007).
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