SummaryAn assay for desoxycortieoster-one-like activity in biological fluids is presented, having a sensitivity in the order of 10 y of DOCA. The critical nature of solvent vehicle choice and of time-dosage of urinary extracts is presented and discussed. Urinary extracts from some edematous patients with heart failure and nephrosis show a sodium-retaining activity greater than that observed in normals and in non-edematous controls.
No takes yet. Share an insight, caveat, or question.
Deming et al. (1950) studied this question.