Key result
Direct hemoperfusion resulted in clinical improvement and recovery within several days in all 7 treated patients with neuroleptic malignant syndrome.
Why the study?
Does direct hemoperfusion improve recovery in patients with Neuroleptic Malignant Syndrome compared to standard medical therapy?
Population
10 patients with Neuroleptic Malignant Syndrome (NMS), 6 of whom presented with respiratory distress
Comparison
Direct hemoperfusion (two to four times) vs Medical management with dantrolene…
Design
Case_series
Authors
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Direct hemoperfusion may hasten recovery in neuroleptic malignant syndrome; leaves open efficacy versus standard therapy in controlled trials.
Observational (n=10)
Does direct hemoperfusion improve recovery in patients with Neuroleptic Malignant Syndrome compared to standard medical therapy?
Direct hemoperfusion may offer rapid clinical improvement and recovery in patients with neuroleptic malignant syndrome compared to standard pharmacotherapy.
Masaji Nishimura (1991) conducted an observational in Neuroleptic Malignant Syndrome (n=10). Direct hemoperfusion vs. Medical therapy (dantrolene, bromocriptine, and other drugs) was evaluated on Clinical improvement and recovery. Direct hemoperfusion resulted in clinical improvement and recovery within several days in all 7 treated patients with neuroleptic malignant syndrome.
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