Key result
Glucocorticoid and immunosuppressant therapy maintained stable lung diffusing capacity (67.5 to 66.9) over 3 years in patients with MCTD and ILD, allowing a significant reduction in GC dose (P=0.007).
Why the study?
Does treatment with glucocorticoids and immunosuppressants stabilize lung function and pulmonary artery pressure in patients with MCTD associated with ILD?
Population
20 patients with mixed connective tissue disease associated with interstitial lung disease diagnosed…
Design
Cohort
Follow-up
three years
Authors
Loading...
In patients with MCTD-associated ILD, long-term therapy with glucocorticoids and immunosuppressants is associated with stable lung function and pulmonary artery pressures over three years.
Observational (n=20)
Does treatment with glucocorticoids and immunosuppressants stabilize lung function and pulmonary artery pressure in patients with MCTD associated with ILD?
In patients with MCTD-associated ILD, long-term therapy with glucocorticoids and immunosuppressants is associated with stable lung function and pulmonary artery pressures over three years.
D. A. Chamberlain (1985) conducted an observational in Mixed connective tissue disease (MCTD) associated with interstitial lung disease (ILD) (n=20). Glucocorticoids and immunosuppressants was evaluated on Course and outcomes of interstitial lung disease (ILD) based on lung function. Glucocorticoid and immunosuppressant therapy maintained stable lung diffusing capacity (67.5 to 66.9) over 3 years in patients with MCTD and ILD, allowing a significant reduction in GC dose (P=0.007).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: