Key result
Hormonal and genetic factors strongly contribute to peripartum cardiomyopathy development and guide clinical management.
This review highlights recent findings on the hormonal and genetic contributions to peripartum cardiomyopathy and their management implications.
May inform risk assessment in peripartum cardiomyopathy; leaves open need for prospective validation before practice change.
Peripartum cardiomyopathy (PPCM) is the unexplained loss of maternal cardiac systolic function in the period surrounding parturition. PPCM affects women worldwide and is a leading cause of maternal mortality. The cause of PPCM has remained elusive until recently. We review here the epidemiology of PPCM, recent findings that strongly indicate hormonal and genetic contributions to the development of PPCM, and implications for the management of women with PPCM.
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Zoltàn Arany (2017) conducted a review in Peripartum cardiomyopathy. Recent findings strongly indicate hormonal and genetic contributions to the development of peripartum cardiomyopathy, with implications for the management of affected women.
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