Chronic stress exposure models influenced hemodynamic responses during stress anticipation (diastolic BP p=0.019, HR p=0.049), and ΔNT-pro-BNP independently predicted peak VO2 (p=0.001).
Observational (n=57)
Does the type of chronic stress exposure influence cardiopulmonary and hormonal responses during stress anticipation?
The type of chronic stress exposure influences hemodynamic responses during physical stress anticipation, and stress hormones like NT-pro-BNP may predict overall cardiopulmonary performance.
p-value: p=0.019, 0.049
Anticipation of stress induces physiological, behavioral and cognitive adjustments that are required for an appropriate response to the upcoming situation. Additional research examining the response of cardiopulmonary parameters and stress hormones during anticipation of stress in different chronic stress adaptive models is needed. As an addition to our previous research, a total of 57 subjects (16 elite male wrestlers, 21 water polo player and 20 sedentary subjects matched for age) were analyzed. Cardiopulmonary exercise testing (CPET) on a treadmill was used as the laboratory stress model; peak oxygen consumption (VO2) was obtained during CPET. Plasma levels of adrenocorticotropic hormone (ACTH), cortisol, alpha-melanocyte stimulating hormone (alpha-MSH) and N-terminal-pro-B type natriuretic peptide (NT-pro-BNP) were measured by radioimmunometric, radioimmunoassay and immunoassay sandwich technique, respectively, together with cardiopulmonary measurements, 10 minutes pre-CPET and at the initiation of CPET. The response of diastolic blood pressure and heart rate was different between groups during stress anticipation (p = 0.019, 0.049, respectively), while systolic blood pressure, peak VO2 and carbon-dioxide production responses were similar. ACTH and cortisol increased during the experimental condition, NT-pro-BNP decreased and alpha-MSH remained unchanged. All groups had similar hormonal responses during stress anticipation with the exception of the ACTH/cortisol ratio. In all three groups, ΔNT-pro-BNP during stress anticipation was the best independent predictor of peak VO2 (B = 36.01, r = 0.37, p = 0.001). In conclusion, the type of chronic stress exposure influences the hemodynamic response during anticipation of physical stress and the path of hormonal stress axis activation. Stress hormones released during stress anticipation may hold predictive value for overall cardiopulmonary performance during the stress condition.
Popović et al. (화요일)은 만성 스트레스 노출 (n=57)에 대한 관찰 연구를 수행했다. 스트레스 기대 중 이완기 혈압과 심박수에 대한 반응에 대해 신체 운동 능력 검사가 신체 활동이 없는 피험자와 비교 평가되었다 (p=0.019, 0.049). 만성 스트레스 노출 모델은 스트레스 기대 중 혈역학적 반응에 영향을 미쳤으며 (이완기 BP p=0.019, HR p=0.049), ΔNT-pro-BNP는 독립적으로 최대 VO2를 예측했다 (p=0.001).