Key result
Metabolically healthy obesity shares adverse cardiometabolic profiles with abnormal obesity, with ~30% having IGT or T2D.
Why the study?
Does metabolically healthy obesity have a more favorable cardiometabolic and inflammatory profile compared to metabolically abnormal obesity?
Cross-Sectional (n=699)
Does metabolically healthy obesity have a more favorable cardiometabolic and inflammatory profile compared to metabolically abnormal obesity?
Metabolically healthy obesity and metabolically abnormal obesity share a similarly adverse cardiometabolic and inflammatory profile, challenging the concept that metabolically healthy obesity is a benign condition.
Questions MHO as benign in practice; challenges the healthy obesity concept yet needs prospective validation.
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Gómez‐Ambrosi et al. (2014) conducted a cross-sectional in Obesity (n=699). Metabolically healthy obesity (MHO) vs. Metabolically abnormal obesity (MAO) and lean subjects was evaluated on Cardiometabolic/inflammatory profile and prevalence of impaired glucose tolerance and type 2 diabetes. Metabolically healthy obesity was associated with a similarly adverse cardiometabolic and inflammatory profile as metabolically abnormal obesity, with >30% of MHO patients exhibiting IGT or T2D.
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