Why the study?
The safety and efficacy of the MitraClip device in advanced and acute heart failure remain a gray zone.
Is emergent MitraClip intervention safe and effective in patients with advanced heart failure and severe mitral regurgitation?
Is emergent MitraClip intervention safe and effective in patients with advanced heart failure and severe mitral regurgitation?
Emergent MitraClip intervention may be a feasible percutaneous treatment option for patients with advanced heart failure and severe functional mitral regurgitation.
May support feasibility of emergent MitraClip in advanced HF; hypothesis-generating and requires prospective trials before adoption.
Mitral regurgitation (MR) is a common valvular disorder often seen in a severely dilated left ventricle (LV) and reduced LV function. In chronic heart failure (HF), severe functional MR increases preload, wall tension, LV workload, and worsening prognosis. The MitraClip device offers a percutaneous treatment option in HF, although its safety and efficacy in advanced and acute HF remain a gray zone. We present a successful case of the emergent MitraClip intervention in a patient with advanced HF and review the relevant literature.
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Cirelli et al. (2025) studied this question.
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