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This study aims to estimate the 5-year age group-specific positives for Pap tests and HPV testing in women aged 30 and older.

Five-Year Experience of Human Papillomavirus DNA and Papanicolaou Test Cotesting

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This study aims to estimate the 5-year age group-specific positives for Pap tests and HPV testing in women aged 30 and older.
Analyzed data from Kaiser Permanente Northern California including 580,289 women who underwent cotesting.
Evaluated test results over five-year age groups from January 2003 to April 2008.
Considered Pap tests positive if interpreted as ASC-US or more severe.
Overall, 6.27% of cotests were HPV positive (95% CI 6.21-6.32%).
3.99% had normal cytology but were HPV positive (95% CI 3.94-4.03%).
5.18% had ASC-US or more severe cytology; 2.87% were HPV negative with ASC-US or more severe cytology.

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Randomized trial estimates HPV and Pap test positives in women aged 30 and older, suggesting minimal concerns over excessive positives.

Castle et al. (2009) studied this question.

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