What question did this study set out to answer?

This study aims to examine the relationship between endometriosis and breakthrough pain during labor epidural analgesia.

May 19, 2026Open Access

Endometriosis and breakthrough pain during labor epidural analgesia: A matched case-control study 2025–2026

Key Points

This study aims to examine the relationship between endometriosis and breakthrough pain during labor epidural analgesia.
Matched case-control design conducted between 2025 and 2026.
Comparison of breakthrough pain incidence in endometriosis cases versus controls.
Data analyzed using adjusted odds ratio (aOR) for breakthrough pain.
Breakthrough pain occurred in 50% of cases with endometriosis compared to 25% of controls.
Adjusted odds ratio indicates increased risk of breakthrough pain in endometriosis patients (aOR 2.99).

Abstract

Tables /Figures: 1 Table,1 figure Endometriosis was previously identified as a potential predictor of breakthrough pain during labor epidural analgesia. In this matched case-control study, breakthrough pain occurred in 50% of cases versus 25% of controls (aOR 2.99). These findings may inform anesthetic counseling and management of endometriosis patients in labor.

Endometriosis and breakthrough pain during labor epidural analgesia: A matched case-control study 2025–2026

Key Points

Abstract

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