Transcatheter aortic valve replacement in low-to-medium surgical risk patients: time for a reappraisal?

Key Points

• The aim is to evaluate the outcomes of transcatheter aortic valve replacement in patients with low-to-medium surgical risk.
• Conducted a randomized trial with participants classified as low-to-medium surgical risk.
• Evaluated clinical outcomes following transcatheter aortic valve replacement.
• Analyzed cardiovascular outcomes and overall mortality.
• The intervention group showed improved cardiovascular outcomes with a hazard ratio (HR) of 0.75, 95% CI 0.60-0.95, p=0.02.
• Overall mortality at one year was reduced to 5% in the intervention group compared to 8% in the control group (p=0.04).
• Patients reported improved quality of life metrics post-procedure.