Why the study?
Data describing how many people worldwide are affected by pulmonary hypertension remain scarce.
Population
Clinical cohort of >500 000 people in Australia combined with 2021 World Bank population estimates
Design
Observational population-based modeling study
Key result
Mild to severe pulmonary hypertension affects an estimated 31.5 million people worldwide (0.616% of men and 0.589% of women aged 20-79), predominantly associated with left heart disease.
Authors
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Substantial global burden linked to left heart disease warrants clinical awareness; leaves open prospective validation and targeted research.
Observational (n=500,000)
Yes
An estimated 31.5 million people worldwide are affected by pulmonary hypertension, with the highest absolute numbers in Asia and highest proportions in Europe.
Strange et al. (2025) conducted an observational in Pulmonary hypertension (n=500,000). Mild to severe pulmonary hypertension affects an estimated 31.5 million people worldwide (0.616% of men and 0.589% of women aged 20-79), predominantly associated with left heart disease.