Key result
Among 80 patients undergoing limb-sparing surgery for soft tissue sarcomas, microscopically positive margins increased local recurrence risk, while high grade and large size reduced survival.
Why the study?
What are the prognostic factors for local recurrence and overall survival in patients undergoing limb-sparing surgery for soft tissue sarcomas?
Population
80 patients who underwent limb-sparing surgery for limb sarcomas
Design
Cohort
Authors
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Positive margins associated with recurrence after limb-sparing sarcoma surgery; hypothesis-generating for grade/size effects on survival.
Cohort (n=80)
What are the prognostic factors for local recurrence and overall survival in patients undergoing limb-sparing surgery for soft tissue sarcomas?
In patients undergoing limb-sparing surgery for soft tissue sarcomas, positive surgical margins increase local recurrence risk, while high tumor grade and large size compromise overall survival.
Rossi et al. (1996) conducted a cohort in Soft tissue sarcomas of the extremities (n=80). Limb-sparing surgery was evaluated on Local recurrence and overall survival. Among 80 patients undergoing limb-sparing surgery for soft tissue sarcomas, microscopically positive margins increased local recurrence risk, while high grade and large size reduced survival.
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