Key result
A rare case of primary dural-based intracranial synovial sarcoma was diagnosed in an elderly man using histological, immunohistochemical, and molecular studies.
Case Report (n=1)
This case report highlights the rare occurrence of primary dura-based intracranial synovial sarcoma, emphasizing the need for a broad differential diagnosis for meningeal spindle cell lesions.
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Should prompt broader dural spindle cell differentials in practice; leaves open optimal management for rare intracranial sarcomas.
The authors present the case of an elderly man with a primary dural-based intracranial synovial sarcoma. Histological and immunohistochemical profiles of the lesion were diagnostic for a synovial sarcoma, and molecular studies using fluorescence in situ hybridization were compatible with a synovial sarcoma. A wide array of spindle cell neoplasms has been described as originating in the dura. To the authors' knowledge, however, this is only the second primary dura-based intracranial synovial sarcoma ever reported, emphasizing the importance of a broad differential diagnosis when encountering spindle cell lesions of the meninges.
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Horbinski et al. (2008) conducted a case report in Primary dural-based intracranial synovial sarcoma (n=1). A rare case of primary dural-based intracranial synovial sarcoma was diagnosed in an elderly man using histological, immunohistochemical, and molecular studies.
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