Key result
Clinically depressed adolescents exhibited significantly higher resting heart rates compared to matched healthy controls, with no other measures of autonomic functioning differentiating the groups.
Why the study?
Does clinical depression affect autonomic cardiac control in adolescents?
Case-Control (n=127)
Does clinical depression affect autonomic cardiac control in adolescents?
Depressed adolescents have higher resting heart rates than healthy peers, a difference not fully explained by autonomic cardiac control, illness severity, or medication effects.
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Elevated resting heart rate in depressed adolescents may flag early CV vulnerability; leaves open autonomic mediation and requires prospective confirmation.
Byrne et al. (2010) conducted a case-control in Depressive disorder (n=127). Clinical depression vs. Nondepressed healthy adolescents was evaluated on Resting measures of heart rate, respiratory sinus arrhythmia, skin conductance level, blood pressure, and pre-ejection period. Clinically depressed adolescents exhibited significantly higher resting heart rates compared to matched healthy controls, with no other measures of autonomic functioning differentiating the groups.
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