Key result
Diffuse omental infiltration on abdominal CT suggested a diagnosis of type 2 diabetes, which completely resolved following one month of treatment with metformin and glipizide.
Why the study?
Does abdominal CT showing diffuse omental infiltration predict the diagnosis of insulin resistant diabetes?
Case Report (n=1)
No
Does abdominal CT showing diffuse omental infiltration predict the diagnosis of insulin resistant diabetes?
Abdominal CT may identify diffuse omental infiltration as a novel imaging sign suggesting undiagnosed type 2 diabetes.
Answers are grounded in this paper and cite their sources.
May suggest undiagnosed diabetes on CT; single case leaves open its predictive value.
We report a diagnosis of diabetes type 2 suggested by diffuse omental infiltration seen on computed tomography which resolved following treatment. There have been reports of increased macrophage infiltration in the omental fat of diabetic patients which we believe is identifiable by CT. To our knowledge, the diagnosis of diabetes with CT has not yet been reported. Diabetes type 2 is commonly a clinical diagnosis. However, undiagnosed diabetic patients may present with nonspecific manifestations and CT may be ordered as part of the initial evaluation. We present a case in which diabetes type 2 was suggested by diffuse omental infiltration.
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Tan et al. (2013) conducted a case report in Type 2 diabetes (n=1). Metformin and glipizide was evaluated on Resolution of omental infiltration on CT and glycemic control. Diffuse omental infiltration on abdominal CT suggested a diagnosis of type 2 diabetes, which completely resolved following one month of treatment with metformin and glipizide.
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