Key result
Individuals with type 2 diabetes mellitus had significantly higher mean visceral fat accumulation (3075.72 cm³ vs 2042.54 cm³) and subcutaneous fat accumulation (3309.39 cm³ vs 1795.75 cm³) compared to non-diabetic controls.
Why the study?
While visceral fat plays a significant role in metabolic syndrome, the effect of subcutaneous fat accumulation remains unclear and warrants investigation, alongside the need for accessible diagnostic tools.
Are visceral and subcutaneous fat accumulations measured by CT scan associated with type 2 diabetes mellitus in a rural Southern Indian population?
Case-Control (n=240)
No
Are visceral and subcutaneous fat accumulations measured by CT scan associated with type 2 diabetes mellitus in a rural Southern Indian population?
Absolute Event Rate: 3075.72% vs 2042.54%
p-value: p=<0.00001
Both visceral and subcutaneous fat accumulation measured by CT are significantly elevated in rural South Indian individuals with type 2 diabetes, suggesting both fat depots are important predictors of metabolic risk.
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SFA effect on T2DM risk remains unclear; leaves open need for prospective validation before any clinical use.
Chincholikar et al. (2025) conducted a case-control in Type 2 diabetes mellitus (n=240). Type 2 diabetes mellitus vs. Without diabetes was evaluated on Mean visceral fat accumulation (VFA) in cm³ (p=<0.00001). Individuals with type 2 diabetes mellitus had significantly higher mean visceral fat accumulation (3075.72 cm³ vs 2042.54 cm³) and subcutaneous fat accumulation (3309.39 cm³ vs 1795.75 cm³) compared to non-diabetic controls.
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