Key result
IL-6 was associated with visceral adiposity and fasting insulin (P<0.01), whereas TNF-alpha was associated with total body fatness and post-challenge insulin (P<0.05).
Population
189 untreated asymptomatic men
Design
Cross-sectional
Authors
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These cross-sectional associations are hypothesis-generating; should not yet change practice or guide cytokine-targeted interventions.
Cross-Sectional (n=189)
Effect estimate: r=0.15-0.32
p-value: p=<0.05
IL-6 is specifically associated with visceral adiposity and hyperinsulinemia, whereas TNF-alpha is associated with total body fatness and insulin resistance in men.
Cartier et al. (2008) conducted a cross-sectional in Visceral adiposity and plasma glucose-insulin homeostasis (n=189). IL-6 and TNF-alpha was evaluated on Association of IL-6 and TNF-alpha with adiposity and plasma glucose-insulin homeostasis (r=0.15-0.32, p=<0.05). IL-6 was associated with visceral adiposity and fasting insulin (P<0.01), whereas TNF-alpha was associated with total body fatness and post-challenge insulin (P<0.05).
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