Bacterial genome sizes, determined by deoxyribonucleic acid reassociation kinetics, vary over a 10-fold range. The smallest studied, Chlamydia trachomatis , had a genome of 6 × 10 5 nucleotide pairs compared to 4.5 × 10 6 for Escherichia coli .
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David T. Kingsbury (1969) studied this question.
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